Immune Oncology

Hypertension and nephrology

DECEMBER 18, 2023

[Cardio-renal-metabolic approach in medicine – thoughts, considerable information based on the new recommendations regarding SGLT2 inhibitors and GLP1 receptor agonists 2. ]

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HUN 2023;27(06)

Clinical Neuroscience

NOVEMBER 30, 2023

Changes in the hippocampal volume in chronic migraine, episodic migraine, and medication overuse headache patients

MAHMUT Nedim AYBAKAN, GIZEM GÜRSOY, NEVIN PAZARCI

Hippocampi are the structures located in the medial depths of both temporal lobes, mainly responsible for memory, navigation and regulation of emotions, and activated during the processing of pain and the modification of nociceptive stimuli. Chronic pain is thought to have stress-like detrimental modulatory effects on the hippocampal neurogenesis, and adults with chronic pain have been showed to have lower hippocampal volumes. a

ENG 2023;76(11-12)

Clinical Neuroscience

NOVEMBER 30, 2023

The effectiveness of organic vegetable oils with high biocompatibility in preventing epidural fibrosis: An experimental study

MEHMET Huseyin AKGUL, MEHMET Yigit AKGUN, TUGCE ANTEPLIOGLU, OGUZ KUL

Epidural fibrosis after all spinal surgeries is an important surgical issue. Various biological and non-biological materials have been tried to inhibit epidural fibrosis, which is deemed to be the most important cause of pain after spinal surgery. Olive oil, nigella sativa oil and soybean oil employed in oral nutrition in clinics involving liquid fatty acids, palmatic acid, linoleic acid, stearic acid and palmitoleic acid.

ENG 2023;76(11-12)

Clinical Neuroscience

NOVEMBER 30, 2023

[Cerebellar antibodies in post-stroke sera of acute ischemic stroke patients]

ATMACA Mert Murat , ERDAĞ Ece , DEMIR Serkan , YÜCEER Hande , ATMACA Çolak Melek , KÜÇÜKALI İsmail Cem , KÜRTÜNCÜ Murat , TÜZÜN Erdem

[Although serum anti-neuronal antibodies are found in acute ischemic stroke patients, it is not completely clear whether they are already present before the cerebrovascular event or emerge thereafter. Sera of 21 consecutive first-ever AIS patients were collected within the first day of AIS, as well as 1 and 6 months after AIS. Well-characterized and novel anti-neuronal antibodies were investigated by cell-based assays, immunoblotting and indirect immunohistochemistry. ]

HUN 2023;76(11-12)

Clinical Neuroscience

NOVEMBER 30, 2023

The significance of neutrophil/lympocyte ratio and platelet/lymphocyte ratio in predicting diabetic polyneuropathy and neuropathic pain severity as inflammatory factors

MUSTAFA TERZI, OZLEM ETHEMOGLU, MEHMET Ali EREN, ÖZCAN KOCATÜRK

Neuropathic pain may appear as one of the first symptoms that take the patient to the physician in type 2 diabetes, which can be asymptomatic for years. Although it is accepted that diabetes is a trigger for vascular inflammation, it has been suggested that inflammation itself may trigger diabetes. In our study, we aimed to investigate the relationship between diabetic polyneuropathy and neuropathic pain and inflammatory markers.

ENG 2023;76(11-12)

Clinical Neuroscience

NOVEMBER 30, 2023

Pembrolizumab-induced peripheral nervous system damage: A combination of myositis/ myasthenia overlap syndrome and motor axonal polyneuropathy

ARMAN ÇAKAR, IBRAHIM KAMACI, ELIF Kocasoy ORHAN, HACER DURMUŞ, YEŞIM PARMAN

Immune-checkpoint inhibitors (ICI) are effective drugs in cancer treatment that block immune checkpoints and stimulate an attack on cancer cells. However, various side effects were reported with ICIs. Peripheral nervous system (PNS) side effects are three times more frequent than those in the central nervous system. A 63-year-old male patient was admitted to our department with a 10-day history of dyspnea, diplopia, and generalized weakness.

ENG 2023;76(11-12)